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Side effects may include nausea, gastrointestinal discomfort, bloating, diarrhea, hives, lower back pain, leg restlessness, numbness, rash, endocrine changes, increased inflammatory response, increased blood urea nitrogen, severe tissue necrosis and venous irritation. Adefovir dipivoxil. The effect of L-carnitine and isoflavone supplementation on weight reduction and visceral fat accumulation in overweight women. Gramignano, G., Lusso, M. R., Madeddu, C., Massa, E., Serpe, R., Deiana, L., Lamonica, G., Dessi, M., Spiga, C., Astara, G., Maccio, A., and Mantovani, G. Efficacy of l-carnitine administration on fatigue, nutritional status, oxidative stress, and related quality of life in 12 advanced cancer patients undergoing anticancer therapy. Double-blind parallel design pilot study of acetyl levocarnitine in patients with Alzheimer's Disease. Passeri M, Cucinotta D, Bonati PA, et al. Muscle carnitine deficiency associated with zidovudine-induced mitochondrial myopathy. However, L-carnitine supplements may raise your blood levels of trimethylamine-N-oxide (TMAO) over time. Musso, G., Gambino, R., Cassader, M., and Pagano, G. A meta-analysis of randomized trials for the treatment of nonalcoholic fatty liver disease. Multicenter trial of L-carnitine in maintenance hemodialysis patients. View abstract. 2010;48(5):503-510. Int J Gynaecol Obstet 2019;147(1):59-64. doi: 10.1002/ijgo.12902. Lai CL, Ahn SH, Lee KS, Um SH, Cho M, Yoon SK, Lee JW, Park NH, Kweon YO, Sohn JH, Lee J, Kim JA, Han KH, Yuen MF. Molyneux, R., Seymour, A. M., and Bhandari, S. Value of carnitine therapy in kidney dialysis patients and effects on cardiac function from human and animal studies. Feinfeld, D. A., Kurian, P., Cheng, J. T., Dilimetin, G., Arriola, M. R., Ward, L., Manis, T., and Carvounis, C. P. Effect of oral L-carnitine on serum myoglobin in hemodialysis patients. World J Gastroenterol. Additionally, the risk of deficiency is higher for those with diseases like cirrhosis and kidney disease. If you've had a seizure before, you should not take carnitine. View abstract. 2006;115(1-2):91-96. Z., Mandalidis, D., Taxildaris, K., and Vargemezis, V. Effects of L-carnitine on oxidative stress responses in patients with renal disease. Acute effect on satiety, resting energy expenditure, respiratory quotient, glucagon-like peptide-1, free fatty acids, and glycerol following consumption of a combination of bioactive food ingredients in overweight subjects. View abstract. L-carnitine is a naturally occurring amino acid derivative thats often taken as a supplement. Acta Urol Ital 1996;10(3):185-187. In general, the adverse effects of oral or intravenous L-carnitine are mild and rare. View abstract. Plochl, E., Sperl, W., Wermuth, B., and Colombo, J. P. [Carnitine deficiency and carnitine therapy in a patient with Rett syndrome]. Anti-human immunodeficiency virus (HIV) activitiy, safety, and pharmacokinetics of adefovir dipivoxyl (9-[2-(bis-pivaloyloxymethyl)-phosphonylmethoxyethyl]adenine) in HIV-infected patients. Biagini, A., Opie, L., Rovai, D., Mazzei, M. G., Carpeggiani, C., and Maseri, A. Additional anti-ischemic effects of long-term L-propionylcarnitine in anginal patients treated with conventional antianginal therapy. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Insomnia; Our bodies partly metabolize carnitine into trimethylamine-N-oxide , which may promote plaque build-up in blood vessels . Van Wouwe JP. View abstract. View abstract. Eur Heart J 1994;15:1267-73. Acute and chronic effects of propionyl-L-carnitine on the hemodynamics, exercise capacity, and hormones in patients with congestive heart failure. View abstract. Acetyl-L-carnitine as a therapeutic agent for mental deterioration in geriatric patients (Double-blind placebo controlled study). Eur.Neuropsychopharmacol. Carnosine is found throughout your body. View abstract. Diabetes Res.Clin Pract.